ABL90 FLEX PLUS blood gas analyser 

When every second counts 

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  • Fast analysis
  • Reliable results
  • Easy to use and maintain

Because speed and efficiency matter

In acute care settings, every second counts and getting reliable information quickly to help your patients is crucial.

If your workflow demands quick analysis, efficiency and extensive insights from small sample sizes, the ABL90 FLEX PLUS is the blood gas analyser for you.

 
 

Easy sample handling

Automatic inlet

 

Easy to use

Video user guidance

 

Automatic Quality Management (AQM)

Automatically initiates and documents corrective actions

 

Consistent sample quality

Standardized automatic mixing

 

Easy to maintain

High-capacity cassettes and easy consumable replacement

Parameters measured

Blood gases: 
pH

Potential of hydrogen

The degree of acidity or alkalinity of any liquid (including blood) is a function of its hydrogen ion concentration [H+], and pH is simply a way of expressing hydrogen ion activity. The relationship between pH and hydrogen ion concentration is described thus:

pH = -log aH+
where aH+ is hydrogen ion activity.

Low pH is associated with acidosis and high pH with alkalosis [1].

Read more

 

1. CLSI. Blood gas and pH analysis and related measurements; Approved Guidelines. CLSI document CA46-A2, 29, 8. Clinical and Laboratory Standards Institute, 940 West Valley Road, Suite 1400, Wayne, Pennsylvania 19087-1898 USA, 2009.

, pCO2

Partial pressure of carbon dioxide

Carbon dioxide (CO2) is an acidic gas; the amount of CO2 in blood is largely controlled by the rate and depth of breathing or ventilation. pCO2 is the partial pressure of CO2 in blood. It is a measure of the pressure exerted by that small portion (~5 %) of total CO2 that remains in the gaseous state, dissolved in the blood plasma. pCO2 is the respiratory component of acid-base balance and reflects the adequacy of pulmonary ventilation. The severity of ventilator failure as well as the chronicity can be judged by the accompanying changes in acid-base status [1].

Read more

 

1. Higgins C. Parameters that reflect the carbon dioxide content of blood. www.acutecaretesting.org Oct 2008.

, pO2

Partial pressure of oxygen

The amount of oxygen in blood is controlled by many variables, e.g. ventilation/perfusion. pO2 is the partial pressure of oxygen in a gas phase in equilibrium with the blood. pO2 only reflects a small fraction (1 – 2 %) of total oxygen in blood that is dissolved in blood plasma [1]. The remaining 98 – 99 % of oxygen present in blood is bound to the hemoglobin in the erythrocytes. pO2 primarily reflects the oxygen uptake in the lungs. 

Read more

 

1. Wettstein R, Wilkins R. Interpretation of blood gases. In: Clinical assessment in respiratory care, 6th ed. St. Louis: Mosby, 2010.

Metabolites: 
cGlu

Glucose

Glucose, the most abundant carbohydrate in human metabolism, serves as the major intracellular energy source (see lactate). Glucose is derived principally from dietary carbohydrate, but it is also produced – primarily in the liver and kidneys – via the anabolic process of gluconeogenesis, and from the breakdown of glycogen (glycogenolysis). This endogenously produced glucose helps keep blood glucose concentration within normal limits, when dietary-derived glucose is not available, e.g. between meals or during periods of starvation.

Read more

, cLac

Lactate

Lactate, the anion that results from dissociation of lactic acid, is an intracellular metabolite of glucose. It is produced by skeletal muscle cells, red blood cells (erythrocytes), the brain, and other tissues during anaerobic energy production (glycolysis). Lactate is formed in the intracellular fluid from pyruvate; the reaction is catalyzed by the enzyme lactate dehydrogenase (LDH) [1].

 

1. Robergs RA, Ghiasvand F, Parker D. Biochemistry of exercise-induced metabolic acidosis. Am J Physiol Regul Integr Comp Physiol 2004; 287: R502-16.

, cCrea

Creatinine

Creatinine is an endogenous waste product of muscle metabolism, derived from creatine, a molecule of major importance for energy production within muscle cells. Creatinine is removed from the body in urine and its concentration in blood reflects glomerular filtration and thereby kidney function.

Read more

, cUrea

Urea


Urea (molecular formula CO(NH2)2) is the principal nitrogenous waste product of protein catabolism, which is eliminated from the body in urine. It is the most abundant organic component of urine. Urea is transported in blood from the liver to the kidneys, where it is filtered from the blood and excreted in the urine. Renal failure is associated with the reduced excretion of urea in urine, and a consequent rise in blood (plasma/serum) urea concentration.

Electrolytes: 
cCa2+

Calcium

The calcium ion (Ca2+) is one of the most prevalent cations in the body, where approximately 1 % is present in the extracellular fluid of blood. Ca2+ plays a vital role for bone mineralization and many cellular processes, e.g. contractility of the heart and the skeletal musculature, neuromuscular transmission, hormone secretion and action in various enzymatic reactions such as, e.g. blood coagulation.

Read more

, cCl-

Chloride

Chloride (Cl-) is the major anion in the extracellular fluid and one of the most important anions in blood. The main function of Cl- is to maintain osmotic pressure, fluid balance, muscular activity, ionic neutrality in plasma, and help elucidate the cause of acid-base disturbances.

Read more

, cK+

Potassium

Potassium (K+) is the major cation in the intracellular fluid, where it has a 25 - 37-fold higher concentration (∼150 mmol/L in tissue cells, ∼105 mmol/L in erythrocytes) than in the extracellular fluid (∼4 mmol/L) [1, 2]. K+ has several vital functions in the body, e.g. regulation of neuromuscular excitability, regulation of heart rhythm, regulation of intracellular and extracellular volume and acid-base status.

Read more

 

1. Burtis CA, Ashwood ER, Bruns DE. Tietz textbook of clinical chemistry and molecular diagnostics. 5th ed. St. Louis: Saunders Elsevier, 2012. Engquist A. Fluids/Electrolytes/Nutrition. 1st ed. Copenhagen: Munksgaard, 1985.
2. Engquist A. Fluids/Electrolytes/Nutrition. 1st ed. Copenhagen: Munksgaard, 1985.

, cNa+

Sodium

Sodium (Na+) is the dominant cation in the extracellular fluid, where it has a 14-fold higher concentration (∼140 mmol/L) than in the intracellular fluid (∼10 mmol/L). Na+ is a major contributor of the osmolality of the extracellular fluid and its main function is largely in controlling and regulating water balance, and maintaining blood pressure. Na+ is also important for transmitting nerve impulses and activating muscle concretion.

Read more

Oximetry: 
COHb

Carboxyhemoglobin

FMetHb is the fraction of total hemoglobin (ctHb) that is present as methemoglobin (MetHb). By convention the fraction is expressed as a percentage (%).

In the range of 0 – 60 % COHb in arterial (COHb(a)) and venous blood (COHb(v)) is similar, i.e. either venous or arterial blood may be analyzed [1]. In most medical texts FCOHb(a) is referred to as simply COHb.

Read more

 

1. Lopez DM, Weingarten-Arams JS, Singer LP, Conway EE Jr. Relationship between arterial, mixed venous and internal jugular carboxyhemoglobin concentrations at low, medium and high concentrations in a piglet model of carbon monoxide toxicity. Crit Care Med 2000; 28: 1998-2001.

, ctBil

Bilirubin

Bilirubin is the yellow breakdown product of the degradation of the heme group of hemoglobin. It is transported in blood from its site of production – the reticuloendothelial system – to the liver, where it is biotransformed before excretion in bile. Jaundice, the pathological yellow discoloration of skin, is due to abnormal accumulation of bilirubin in the tissues, and is always associated with elevated blood concentration of bilirubin (hyperbilirubinemia).

Read more

, ctHb

Total hemoglobin

The concentration of total hemoglobin (ctHb) in blood includes oxyhemoglobin (cO2Hb), deoxyhemoglobin (cHHb), as well as the dysfunctional hemoglobin species that are incapable of binding oxygen:

carboxyhemoglobin (cCOHb) (see COHb), methemoglobin (cMetHb) (see MetHb) and sulfhemoglobin (cSulfHb).

Thus:

ctHb = cO2Hb + cHHb + cCOHb + cMetHb + cSulfHb

The rare sulfHb is not included in the reported c tHb in most oximeters.

Read more

, FHbF

Fraction of fetal hemoglobin

FHbF in total hemoglobin in blood.

Read more

, FHHb

Fraction of deoxyhemoglobin


FHHb in total hemoglobin in blood.

, MetHb

Methemoglobin

FMetHb is the fraction of total hemoglobin (ctHb) that is present as methemoglobin (MetHb). By convention the fraction is expressed as a percentage (%) [1].

In most medical text boxes MetHb(a) is referred to as simply methemoglobin (MetHb).

Read more

 

1. CLSI. Blood gas and pH analysis and related measurements; Approved Guidelines. CLSI document CA46-A2, 29, 8. Clinical and Laboratory Standards Institute, 940 West Valley Road, Suite 1400, Wayne, Pennsylvania 19087-1898 USA, 2009.

, sO2

Oxygen saturation

Oxygen saturation (sO2) is the ratio of oxyhemoglobin concentration to concentration of functional hemoglobin (i.e. oxyhemoglobin (O2Hb) and deoxyhemoglobin (HHb) capable of carrying oxygen [1].

The sO2 reflects utilization of the currently available oxygen transport capacity.

In arterial blood 98 – 99 % of oxygen is transported in erythrocytes bound to hemoglobin. The remaining 1–2 % of the oxygen transported in blood is dissolved in the blood plasma – this is the portion reported as partial pressure of oxygen (pO2) [2].

Read more

 

1. CLSI. Blood gas and pH analysis and related measurements; Approved Guidelines. CLSI document CA46-A2, 29, 8. Clinical and Laboratory Standards Institute, 940 West Valley Road, Suite 1400, Wayne, Pennsylvania 19087-1898 USA, 2009.
2. Higgins C. Parameters that reflect the carbon dioxide content of blood. www.acutecaretesting.org Oct 2008.

, FO2Hb

Fraction of oxyhemoglobin

FO2Hb in total hemoglobin in blood.

Read more

Close

Fast analysis of up to 19 parameters

The ABL90 FLEX PLUS delivers test results in just 35 seconds on up to 19 vital parameters, including creatinine and urea - all from one blood sample of only 65 µL*. 

With a high uptime of more than 23.5 hours per day and only 60 seconds between each sample measurement, the analyser is quickly ready for you to test the next sample*.

*See specifications for ABL90 FLEX PLUS configured with and without creatinine and urea
ABL90 FLEX PLUS specifications With creatinine and urea Without creatinine and urea
No. of parameters 19 17
Uptime   > 23 hours > 23.5 hours
Amount of blood sample needed 65 µL 45 µL
Time between sample measurement 120 seconds 60 seconds

Reliable results

The ABL90 FLEX PLUS delivers lab-quality results at the point of care for more confident treatment decisions. Continuous automatic quality management (AQM) provides automatic quality control, continuous checks and automatically initiates and documents corrective actions.

In addition, automatic patient registration, automatic sample mixing, and safePICO syringes help reduce the risk of patient sample mix up and preanalytical errors.

Easy to use and maintain

The ABL90 FLEX PLUS blood gas analyser is designed to be easy to use and maintain so your staff spend less time in front of the analyser. Instructional videos provide on-screen guidance for operation and maintenance.

And, with only two consumables to replace, remote service and full IT connectivity, your ABL90 FLEX PLUS blood gas analyser is ready when you are—whether it’s in the lab or at the point of care.

Patient safety is at the centre of everything we do and determines the procedures, our activities and all other actions performed in the ED.

- ED Director, Axel Plessman, ED director at the DRK Hospital Group in Thüringen, Germany

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Built-in cybersecurity

The ABL90 FLEX PLUS is built on the Radiometer cyber security model, which works alongside hospital security measures in a series of defense layers.

These defense layers help prevent cyber attacks from compromising patient data and analyser performance. For extra protection, Security packages update analysers’ security levels throughout their lifetime.

Get the latest Microsoft supported operating system, patches for ongoing security upgrades, and proactive protection with Application Control. Visit Security packages to learn more.

Download technical paper

Our seamless solution

Centralized control with AQURE

AQURE provides you with a complete overview and access to manage the performance of your POC IT setup. Learn more about how AQURE can work for you.
More information

Blood gas syringes and capillary tubes

Meet your blood sampling needs with our samplers, designed to facilitate reliable test results.
More information

QC ampoules for blood gas analysers

Automate and simplify QC procedures for acute care diagnostics and support regulatory compliance.
More information

Related knowledge sources

Get the acute care testing handbook

Download the free guide on blood gases and other critical parameters in acute care testing.
Download now

Guiding your blood gas testing

Through three educational videos, you’ll experience why blood gas analysis is important in three critical patient cases covering COPD, intoxication and sepsis. Further, a set of three how-to videos will guide you in performing an arterial puncture, understanding the acid-base balance in the blood and to reading the blood gas report.
Watch the blood gas tutorial videos

Let us help you prevent preanalytical errors

Find out more about the most common preanalytical errors and how to prevent them.
Read more
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