Reducing hemolysis in blood samples
Vigorous shaking during mixing or transport might lead to a hemolyzed blood gas sample [1]
Hemolysis mixing in blood samples with automatic mixing
Additionally, hemolysis in blood gas samples can occur through vigorous mixing prior to analysis. [2]
Automatic mixing on a blood gas analyzer is preferable to non-standardized manual mixing. This is because the automatic mixing helps ensure sufficient mixing and a homogenous sample. [3 - 4]
Dry electrolyte balanced heparin in combination with automatic mixing in our safePICO syringes help reduce the risk of blood sample clotting.
Prior to analysis, sufficient mixing is crucial to obtain a homogeneous sample. The safePICO syringe and automatic mixing on a blood gas analyzer helps you produce a homogeneous sample, without causing hemolysis. [3]
The safePICO syringe is designed to reduce the risk of other preanalytical errors. In addition to hemolysis during mixing, safePICO can help to remove air bubbles safely from the sample and to reduce the risk of needlestick injuries, a clotted blood sample, or patient-sample mix-up.
References
2. Lippi G, Fontana R, Avanzani P et al. Influence of spurious hemolysis on blood gas analysis. Clin Chem Lab Med 2013; 51: 1651-4.
3. Grenache D et al. Integrated and automatic mixing of whole blood: An evaluation of a novel blood gas analyzer. Science Direct 2006; 375, 1-2; 153 – 157
4. Benoit M et al. Evaluation and advantages of an automatic magnetic mixing of syringes integrated with a whole blood gas analyzer. Scandinavian Journal of Clinical & Laboratory Investigation 2009; 69, 5: 628-32.
5. Dukic L et al. Blood gas testing and related measurements: National recommendations on behalf of the Croatian Society of Medical Biochemistry and Laboratory Medicine. Biochemia Medica 2016; 26, 3: 318-36.
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